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The yeast HPR1 gene has a functional role in transcriptional elongation that uncovers a novel source of genome instability

The yeast HPR1 gene plays an important role in genome stability, as indicated by the observation that hpr1 mutants have high frequencies of DNA repeat recombination and chromosome loss. Here we report that HPR1 is required for transcriptional elongation. Transcription driven from constitutive and re...

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Bibliografiske detaljer
Udgivet i:Genes Dev
Principais autores: Chávez, Sebastián, Aguilera, Andrés
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 1997
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316820/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9407037/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.11.24.3459
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