Inferring condition-specific modulation of transcription factor activity in yeast through regulon-based analysis of genomewide expression.
A key goal of systems biology is to understand how genomewide mRNA expression levels are controlled by transcription factors (TFs) in a condition-specific fashion. TF activity is frequently modulated at the post-translational level through ligand binding, covalent modification, or changes in sub-cel...
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| Principais autores: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science (PLoS)
2008-09-01
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| Serier: | PLoS ONE |
| Online adgang: | http://europepmc.org/articles/PMC2518834?pdf=render |
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