Cytolethal distending toxin: a conserved bacterial genotoxin that blocks cell cycle progression, leading to apoptosis of a broad range of mammalian cell lineages

Cytolethal distending toxin (CDT) is a heterotrimeric AB-type genotoxin produced by several clinically important Gram-negative mucocutaneous bacterial pathogens. Irrespective of the bacterial species of origin, CDT causes characteristic and irreversible cell cycle arrest and apoptosis in a broad ran...

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Detaylı Bibliyografya
Asıl Yazarlar: Jinadasa, Rasika N., Bloom, Stephen E., Weiss, Robert S., Duhamel, Gerald E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for General Microbiology 2011
Konular:
Review
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167888/
https://ncbi.nlm.nih.gov/pubmed/21565933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.049536-0
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