A Neutralizing RNA Aptamer against EGFR Causes Selective Apoptotic Cell Death

Nucleic acid aptamers have been developed as high-affinity ligands that may act as antagonists of disease-associated proteins. Aptamers are non immunogenic and characterised by high specificity and low toxicity thus representing a valid alternative to antibodies or soluble ligand receptor traps/deco...

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Detalhes bibliográficos
Main Authors: Esposito, Carla Lucia, Passaro, Diana, Longobardo, Immacolata, Condorelli, Gerolama, Marotta, Pina, Affuso, Andrea, de Franciscis, Vittorio, Cerchia, Laura
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167817/
https://ncbi.nlm.nih.gov/pubmed/21915281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024071
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