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Statistical methodology for the evaluation of vaccine efficacy in a phase III multi-centre trial of the RTS,S/AS01 malaria vaccine in African children

BACKGROUND: There has been much debate about the appropriate statistical methodology for the evaluation of malaria field studies and the challenges in interpreting data arising from these trials. METHODS: The present paper describes, for a pivotal phase III efficacy of the RTS, S/AS01 malaria vaccin...

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Detalhes bibliográficos
Main Authors: Lievens, Marc, Aponte, John J, Williamson, John, Mmbando, Bruno, Mohamed, Ali, Bejon, Philip, Leach, Amanda
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167766/
https://ncbi.nlm.nih.gov/pubmed/21816030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-10-222
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