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A ribosomal function is necessary for efficient splicing of the T4 phage thymidylate synthase intron in vivo
Splicing of the group I intron of the T4 thymidylate synthase (td) gene was uncoupled from translation by introducing stop codons in the upstream exon. This resulted in severe splicing deficiency in vivo. Overexpression of a UGA suppressor tRNA partially rescued splicing, suggesting that this in vit...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Genes Dev |
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| Κύριοι συγγραφείς: | , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Cold Spring Harbor Laboratory Press
1998
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316773/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573049/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.9.1327 |
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