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Direct interaction of hematopoietic transcription factors PU.1 and GATA-1: functional antagonism in erythroid cells

Malignant transformation usually inhibits terminal cell differentiation but the precise mechanisms involved are not understood. PU.1 is a hematopoietic-specific Ets family transcription factor that is required for development of some lymphoid and myeloid lineages. PU.1 can also act as an oncoprotein...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Genes Dev
Hauptverfasser: Rekhtman, Natasha, Radparvar, Farshid, Evans, Todd, Skoultchi, Arthur I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316770/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10364157/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.13.11.1398
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