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Ligand-dependent repression of the erythroid transcription factor GATA-1 by the estrogen receptor.

High-dose estrogen administration induces anemia in mammals. In chickens, estrogens stimulate outgrowth of bone marrow-derived erythroid progenitor cells and delay their maturation. This delay is associated with down-regulation of many erythroid cell-specific genes, including alpha- and beta-globin,...

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Detalhes bibliográficos
Main Authors: Blobel, G A, Sieff, C A, Orkin, S H
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC230546/
https://ncbi.nlm.nih.gov/pubmed/7760810
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