Tripartite Control of Dynamic ACTH-Cortisol Dose Responsiveness by Age, Body Mass Index, and Gender in 111 Healthy Adults

BACKGROUND: Recent analyses in small cohorts suggest that pituitary hormones exert time-varying (viz., initial and delayed) dynamic dose-responsive effects on target glands, wherein down-regulating dynamics are inferable on a time scale of single pulses. HYPOTHESIS: Age, body mass index (BMI), and s...

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Bibliographische Detailangaben
Hauptverfasser: Veldhuis, Johannes D., Iranmanesh, Ali, Roelfsema, Ferdinand, Aoun, Paul, Takahashi, Paul, Miles, John M., Keenan, Daniel M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2011
Schlagworte:
Endocrine Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167672/
https://ncbi.nlm.nih.gov/pubmed/21752885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2011-0084
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