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Vascular cell-adhesion molecule-1 plays a central role in the proangiogenic effects of oxidative stress

Oxidative stress exacerbates neovascularization (NV) in many disease processes. In this study we investigated the mechanism of that effect. Mice deficient in superoxide dismutase 1 (Sod1(−/−) mice) have increased oxidative stress and show severe ocular NV that is reduced to baseline by antioxidants....

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Detalhes bibliográficos
Principais autores: Dong, Aling, Shen, Jikui, Zeng, MingBing, Campochiaro, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167513/
https://ncbi.nlm.nih.gov/pubmed/21844360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012859108
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