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Transgene-mediated cosuppression in the C. elegans germ line

Functional silencing of chromosomal loci can be induced by transgenes (cosuppression) or by introduction of double-stranded RNA (RNAi). Here, we demonstrate the generality of and define rules for a transgene-mediated cosuppression phenomenon in the Caenorhabditis elegans germ line. Functional repres...

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Bibliographic Details
Main Authors: Dernburg, Abby F., Zalevsky, Jonathan, Colaiácovo, Mónica P., Villeneuve, Anne M.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2000
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC316736/
https://ncbi.nlm.nih.gov/pubmed/10887151
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