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The chromosome axis mediates feedback control of CHK-2 to ensure crossover formation in C. elegans
CHK-2 kinase is a master regulator of meiosis in C. elegans. Its activity is required for homolog pairing and synapsis and for double-strand break formation, but how it drives and coordinates these pathways to ensure crossover formation remains unknown. Here we show that CHK-2 promotes pairing and s...
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| Publicado en: | Dev Cell |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4624198/ https://ncbi.nlm.nih.gov/pubmed/26506311 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2015.09.021 |
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