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Transgene-mediated cosuppression and RNA interference enhance germ-line apoptosis in Caenorhabditis elegans

Introduction of multiple copies of a germ-line–expressed gene elicits silencing of the corresponding endogenous gene during Caenorhabditis elegans oogenesis; this process is referred to as germ-line cosuppression. Transformed plasmids assemble into extrachromosomal arrays resembling extra minichromo...

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Bibliografische gegevens
Hoofdauteurs: Adamo, Adele, Woglar, Alexander, Silva, Nicola, Penkner, Alexandra, Jantsch, Verena, La Volpe, Adriana
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295272/
https://ncbi.nlm.nih.gov/pubmed/22331911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1107390109
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