Different prelamin A forms accumulate in human fibroblasts: a study in experimental models and progeria

Lamin A is a component of the nuclear lamina mutated in a group of human inherited disorders known as laminopathies. Among laminopathies, progeroid syndromes and lipodystrophies feature accumulation of prelamin A, the precursor protein which, in normal cells, undergoes a multi-step processing to yie...

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Библиографические подробности
Главные авторы: Dominici, S., Fiori, V., Magnani, M., Schena, E., Capanni, C., Camozzi, D., D’Apice, M.R., Le Dour, C., Auclair, M., Caron, M., Novelli, G., Vigouroux, C., Maraldi, N.M., Lattanzi, G.
Формат: Artigo
Язык:Inglês
Опубликовано: PAGEPress Publications 2009
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167279/
https://ncbi.nlm.nih.gov/pubmed/30256865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/ejh.2009.e6
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