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Different prelamin A forms accumulate in human fibroblasts: a study in experimental models and progeria
Lamin A is a component of the nuclear lamina mutated in a group of human inherited disorders known as laminopathies. Among laminopathies, progeroid syndromes and lipodystrophies feature accumulation of prelamin A, the precursor protein which, in normal cells, undergoes a multi-step processing to yie...
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Main Authors: | , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
PAGEPress Publications
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3167279/ https://ncbi.nlm.nih.gov/pubmed/30256865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4081/ejh.2009.e6 |
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