A specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targeting

Homozygous E2F-5 knockout embryos and mice have been generated. Although embryonic development appeared normal, newborn mice developed nonobstructive hydrocephalus, suggesting excessive cerebrospinal fluid (CSF) production. Although the CSF-producing choroid plexus displayed normal cellular organiza...

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Bibliographische Detailangaben
Hauptverfasser: Lindeman, Geoffrey J., Dagnino, Lina, Gaubatz, Stefan, Xu, Yuhui, Bronson, Roderick T., Warren, Henry B., Livingston, David M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1998
Schlagworte:
Research Communication
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316727/
https://ncbi.nlm.nih.gov/pubmed/9553039
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