A specific, nonproliferative role for E2F-5 in choroid plexus function revealed by gene targeting

Homozygous E2F-5 knockout embryos and mice have been generated. Although embryonic development appeared normal, newborn mice developed nonobstructive hydrocephalus, suggesting excessive cerebrospinal fluid (CSF) production. Although the CSF-producing choroid plexus displayed normal cellular organiza...

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Detalles Bibliográficos
Publicado en:Genes Dev
Main Authors: Lindeman, Geoffrey J., Dagnino, Lina, Gaubatz, Stefan, Xu, Yuhui, Bronson, Roderick T., Warren, Henry B., Livingston, David M.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1998
Assuntos:
Research Communication
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316727/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9553039/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.12.8.1092
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