The miR-15 Family Regulates Post-natal Mitotic Arrest of Cardiomyocytes

RATIONALE: Mammalian cardiomyocytes withdraw from the cell cycle during early post-natal development, which significantly limits the capacity of the adult mammalian heart to regenerate following injury. The regulatory mechanisms which govern cardiomyocyte cell cycle withdrawal and binucleation are p...

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Библиографические подробности
Главные авторы: Porrello, Enzo R., Johnson, Brett A., Aurora, Arin B., Simpson, Emma, Nam, Young-Jae, Matkovich, Scot J., Dorn, Gerald W., van Rooij, Eva, Olson, Eric N.
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167208/
https://ncbi.nlm.nih.gov/pubmed/21778430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.111.248880
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