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The subnuclear organization of histone gene regulatory proteins and 3′ end processing factors of normal somatic and embryonic stem cells is compromised in selected human cancer cell types

Human histone gene expression is controlled at the level of transcription initiation and subsequent 3′end processing to generate non-polyadenylated stem-loop containing histone mRNAs. Transcription is controlled at the G1/S phase transition by the Cyclin E/CDK2 mediated induction of p220(NPAT)/HiNF-...

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Dettagli Bibliografici
Autori principali: Ghule, Prachi N., Dominski, Zbigniew, Lian, Jane B., Stein, Janet L., van Wijnen, Andre J., Stein, Gary S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167205/
https://ncbi.nlm.nih.gov/pubmed/19277982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.21740
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