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Spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns

BACKGROUND: In cerebrospinal fluid (CSF), which is a rich source of biomarkers for neurological diseases, identification of biomarkers requires methods that allow reproducible detection of low abundance proteins. It is therefore crucial to decrease dynamic range and improve assessment of protein abu...

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Detalhes bibliográficos
Main Authors: Borg, Jacques, Campos, Alex, Diema, Claudio, Omeñaca, Núria, de Oliveira, Eliandre, Guinovart, Joan, Vilaseca, Marta
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167203/
https://ncbi.nlm.nih.gov/pubmed/21906361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1559-0275-8-6
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