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Spectral counting assessment of protein dynamic range in cerebrospinal fluid following depletion with plasma-designed immunoaffinity columns

BACKGROUND: In cerebrospinal fluid (CSF), which is a rich source of biomarkers for neurological diseases, identification of biomarkers requires methods that allow reproducible detection of low abundance proteins. It is therefore crucial to decrease dynamic range and improve assessment of protein abu...

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Main Authors: Borg, Jacques, Campos, Alex, Diema, Claudio, Omeñaca, Núria, de Oliveira, Eliandre, Guinovart, Joan, Vilaseca, Marta
Formáid: Artigo
Teanga:Inglês
Foilsithe: Springer 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3167203/
https://ncbi.nlm.nih.gov/pubmed/21906361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1559-0275-8-6
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