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NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway

The conserved Hippo signaling pathway regulates organ size in Drosophila melanogaster and mammals and has an essential role in tumor suppression and the control of cell proliferation. Recent studies identified activators of Hippo signaling, but antagonists of the pathway have remained largely elusiv...

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Detalhes bibliográficos
Main Authors: Habbig, Sandra, Bartram, Malte P., Müller, Roman U., Schwarz, Ricarda, Andriopoulos, Nikolaos, Chen, Shuhua, Sägmüller, Josef G., Hoehne, Martin, Burst, Volker, Liebau, Max C., Reinhardt, H. Christian, Benzing, Thomas, Schermer, Bernhard
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166863/
https://ncbi.nlm.nih.gov/pubmed/21555462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201009069
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