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CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

Cellular stress, particularly in response to toxic and metabolic insults that perturb function of the endoplasmic reticulum (ER stress), is a powerful inducer of the transcription factor CHOP. The role of CHOP in the response of cells to injury associated with ER stress was examined in a murine defi...

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Main Authors: Zinszner, Helene, Kuroda, Masahiko, Wang, XiaoZhong, Batchvarova, Nikoleta, Lightfoot, Richard T., Remotti, Helen, Stevens, James L., Ron, David
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC316680/
https://ncbi.nlm.nih.gov/pubmed/9531536
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