Activation of Stress Kinases in the Brain of Mucopolysaccharidosis IIIB mice

The accumulation of heparan sulfate (HS) in lysosomes is the primary consequence of the enzyme defect (α-N-acetylglucosaminidase) in mucopolysaccharidosis type IIIB. This accumulation triggers a cascade of pathological events that progressively leads to CNS pathology. Here we examined the activation...

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Detaylı Bibliyografya
Asıl Yazarlar: Cecere, Francesca, Di Domenico, Carmela, Di Napoli, Daniele, Boscia, Francesca, Di Natale, Paola
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Wiley Subscription Services, Inc., A Wiley Company 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166654/
https://ncbi.nlm.nih.gov/pubmed/21618584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22674
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