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Activation of Stress Kinases in the Brain of Mucopolysaccharidosis IIIB mice
The accumulation of heparan sulfate (HS) in lysosomes is the primary consequence of the enzyme defect (α-N-acetylglucosaminidase) in mucopolysaccharidosis type IIIB. This accumulation triggers a cascade of pathological events that progressively leads to CNS pathology. Here we examined the activation...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166654/ https://ncbi.nlm.nih.gov/pubmed/21618584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jnr.22674 |
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