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HIV Protease Inhibitors Alter Innate Immune Response Signaling to dsRNA in Oral Epithelial Cells: Implications for IRIS?
In this investigation several HIV protease inhibitors (PIs) altered the virally associated, dsRNA- stimulated, innate immune response. Lopinavir, the most potent inducer of IL-8 expression, also inhibited dsRNA-induced MCP-1 expression. Further analyses demonstrated that NF-κB is required for lopina...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166643/ https://ncbi.nlm.nih.gov/pubmed/20841991 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32833f4022 |
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