Gross chromosomal rearrangements and genetic exchange between nonhomologous chromosomes following BRCA2 inactivation

Cancer-causing mutations often arise from gross chromosomal rearrangements (GCRs) such as translocations, which involve genetic exchange between nonhomologous chromosomes. Here we show that murine Brca2 has an essential function in suppressing GCR formation after chromosome breakage. Cells that harb...

Deskribapen osoa

Xehetasun bibliografikoak

Argitaratua izan da:	Genes Dev
Egile Nagusiak:	Yu, Veronica P.C.C., Koehler, Michael, Steinlein, Claus, Schmid, Michael, Hanakahi, Leslyn A., van Gool, Alain J., West, Stephen C., Venkitaraman, Ashok R.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Cold Spring Harbor Laboratory Press 2000
Gaiak:	Research Paper
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316655/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10837032/
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!