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Rescue of osteoclast function by transgenic expression of kinase-deficient Src in src−/− mutant mice

The Src tyrosine kinase has been implicated in a wide variety of signal transduction pathways, yet despite the nearly ubiquitous expression of c-src, src−/− mice show only one major phenotype—osteopetrosis caused by an intrinsic defect in osteoclasts, the cells responsible for resorbing bone. To exp...

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Bibliografski detalji
Glavni autori: Schwartzberg, Pamela L., Xing, Lianping, Hoffmann, Oskar, Lowell, Clifford A., Garrett, Lisa, Boyce, Brendan F., Varmus, Harold E.
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 1997
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC316651/
https://ncbi.nlm.nih.gov/pubmed/9353253
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