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Combination Treatment with Low-dose Niaspan and Tissue Plasminogen Activator Provides Neuroprotection after Embolic Stroke in Rats

INTRODUCTION: Niaspan, an extended-release formulation of Niacin (vitamin B3), has been widely used to increase high density lipoprotein (HDL) cholesterol and to prevent cardiovascular diseases and stroke. We have previously demonstrated that Niaspan (40mg/kg) administered at 2 hours after stroke in...

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Bibliographische Detailangaben
Hauptverfasser: Shehadah, Amjad, Chen, Jieli, Cui, Yisheng, Zhang, Li, Roberts, Cynthia, Lu, Mei, Chopp, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166443/
https://ncbi.nlm.nih.gov/pubmed/21802695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2011.07.008
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