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Combination Treatment with Low-dose Niaspan and Tissue Plasminogen Activator Provides Neuroprotection after Embolic Stroke in Rats

INTRODUCTION: Niaspan, an extended-release formulation of Niacin (vitamin B3), has been widely used to increase high density lipoprotein (HDL) cholesterol and to prevent cardiovascular diseases and stroke. We have previously demonstrated that Niaspan (40mg/kg) administered at 2 hours after stroke in...

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Detalhes bibliográficos
Main Authors: Shehadah, Amjad, Chen, Jieli, Cui, Yisheng, Zhang, Li, Roberts, Cynthia, Lu, Mei, Chopp, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166443/
https://ncbi.nlm.nih.gov/pubmed/21802695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2011.07.008
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