Combination Treatment with Low-dose Niaspan and Tissue Plasminogen Activator Provides Neuroprotection after Embolic Stroke in Rats

INTRODUCTION: Niaspan, an extended-release formulation of Niacin (vitamin B3), has been widely used to increase high density lipoprotein (HDL) cholesterol and to prevent cardiovascular diseases and stroke. We have previously demonstrated that Niaspan (40mg/kg) administered at 2 hours after stroke in...

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Bibliographic Details
Main Authors: Shehadah, Amjad, Chen, Jieli, Cui, Yisheng, Zhang, Li, Roberts, Cynthia, Lu, Mei, Chopp, Michael
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166443/
https://ncbi.nlm.nih.gov/pubmed/21802695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jns.2011.07.008
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