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A Cell-Permeable Phosphine-Borane Complex Delays Retinal Ganglion Cell Death After Axonal Injury Through Activation of The Pro-Survival extracellular signal-regulated kinases 1/2 Pathway

The reactive oxygen species superoxide has been recognized as a critical signal triggering retinal ganglion cell (RGC) death after axonal injury. Although the downstream targets of superoxide are unknown, chemical reduction of oxidized sulfhydryls has been shown to be neuroprotective for injured RGC...

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Detalhes bibliográficos
Main Authors: Almasieh, Mohammadali, Lieven, Christopher J., Levin, Leonard A., Di Polo, Adriana
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166386/
https://ncbi.nlm.nih.gov/pubmed/21749374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07382.x
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