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Dimerization of the DYT6 dystonia protein, THAP1, requires residues within the coiled-coil domain

THAP1 is a DNA binding protein that has been recently associated with DYT6 dystonia, a hereditary movement disorder involving sustained, involuntary muscle contractions. A large number of dystonia-related mutations have been identified in THAP1 in diverse patient populations worldwide. Previous repo...

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Bibliografische gegevens
Hoofdauteurs: Sengel, Cem, Gavarini, Sophie, Sharma, Nutan, Ozelius, Laurie J., Bragg, D. Cristopher
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166381/
https://ncbi.nlm.nih.gov/pubmed/21752024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2011.07386.x
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