Effectiveness of CID, HCD, and ETD with FT MS/MS for degradomic-peptidomic analysis: comparison of peptide identification methods

We report on the effectiveness of CID, HCD, and ETD for LC-FT MS/MS analysis of peptides using a tandem linear ion trap-Orbitrap mass spectrometer. A range of software tools and analysis parameters were employed to explore the use of CID, HCD, and ETD to identify peptides isolated from human blood p...

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Detalhes bibliográficos
Main Authors: Shen, Yufeng, Tolić, Nikola, Xie, Fang, Zhao, Rui, Purvine, Samuel O., Schepmoes, Athena A., Ronald, J. Moore, Anderson, Gordon A., Smith, Richard D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166380/
https://ncbi.nlm.nih.gov/pubmed/21678914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr200052c
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