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Relative Quantification: Characterization of bias, variability and fold changes in mass spectrometry data from iTRAQ labeled peptides

Shotgun proteomics via mass spectrometry (MS) is a powerful technology for biomarker discovery which has the potential to lead to non-invasive disease screening mechanisms. Successful application of MS-based proteomics technologies for biomarker discovery requires accurate expectations of bias, repr...

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Detalhes bibliográficos
Main Authors: Mahoney, Douglas W., Therneau, Terry M., Heppelmann, Carrie J., Higgins, LeeAnn, Benson, Linda M., Zenka, Roman M., Jagtap, Pratik, Nelsestuen, Gary L., Bergen, H. Robert, Oberg, Ann L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166364/
https://ncbi.nlm.nih.gov/pubmed/21755926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr2001308
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