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Elastase Inhibitory Activity of Airway α1-Antitrypsin is Protected by Treatment with a Catalytic Antioxidant in a Baboon Model of Severe Bronchopulmonary Dysplasia

Recent studies in animal models of bronchopulmonary dysplasia (BPD) suggest that antioxidant treatments may be beneficial for the disease. However, the mechanisms by which these drugs improve the course of BPD are not completely known. Alpha1-antitrypsin (α1-AT) is one of the major serine protease i...

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Bibliografske podrobnosti
Main Authors: Karaaslan, Çagatay, Hirakawa, Hiroshi, Yasumatsu, Ryuji, Chang, Ling-Yi L., Pierce, Richard A, Crapo, James D., Cataltepe, Sule
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166355/
https://ncbi.nlm.nih.gov/pubmed/21705962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e31822a357e
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