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Elastase Inhibitory Activity of Airway α1-Antitrypsin is Protected by Treatment with a Catalytic Antioxidant in a Baboon Model of Severe Bronchopulmonary Dysplasia

Recent studies in animal models of bronchopulmonary dysplasia (BPD) suggest that antioxidant treatments may be beneficial for the disease. However, the mechanisms by which these drugs improve the course of BPD are not completely known. Alpha1-antitrypsin (α1-AT) is one of the major serine protease i...

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Detalhes bibliográficos
Main Authors: Karaaslan, Çagatay, Hirakawa, Hiroshi, Yasumatsu, Ryuji, Chang, Ling-Yi L., Pierce, Richard A, Crapo, James D., Cataltepe, Sule
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166355/
https://ncbi.nlm.nih.gov/pubmed/21705962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e31822a357e
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