Functional Polymorphism of the Mu-Opioid Receptor Gene (OPRM1) Influences Reinforcement Learning in Humans

Previous reports on the functional effects (i.e., gain or loss of function), and phenotypic outcomes (e.g., changes in addiction vulnerability and stress response) of a commonly occurring functional single nucleotide polymorphism (SNP) of the mu-opioid receptor (OPRM1 A118G) have been inconsistent....

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Autors principals: Lee, Mary R., Gallen, Courtney L., Zhang, Xiaochu, Hodgkinson, Colin A., Goldman, David, Stein, Elliot A., Barr, Christina S.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166306/
https://ncbi.nlm.nih.gov/pubmed/21912675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024203
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