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Rational Design of Temperature-Sensitive Alleles Using Computational Structure Prediction
Temperature-sensitive (ts) mutations are mutations that exhibit a mutant phenotype at high or low temperatures and a wild-type phenotype at normal temperature. Temperature-sensitive mutants are valuable tools for geneticists, particularly in the study of essential genes. However, finding ts mutation...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3166291/ https://ncbi.nlm.nih.gov/pubmed/21912654 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0023947 |
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