H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19

H19 and Igf2 are expressed in a monoallelic fashion from the maternal and paternal chromosomes, respectively. A region upstream of H19 has been shown to regulate such imprinted expression of both genes in cis. We have taken advantage of a loxP/cre recombinase-based strategy to delete this region in...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Srivastava, Madhulika, Hsieh, Sandra, Grinberg, Alexander, Williams-Simons, Lisa, Huang, Sing-Ping, Pfeifer, Karl
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2000
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316622/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10817754/
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