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Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast

The MAP kinase Hog1 transiently accumulates in the nucleus upon activation. Although Hog1 nuclear export correlates with its dephosphorylation, we find that dephosphorylation is not necessary for export. Unexpectedly, a strain lacking the nuclear protein tyrosine phosphatase, Ptp2, showed decreased...

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Détails bibliographiques
Publié dans:Genes Dev
Auteurs principaux: Mattison, Christopher P., Ota, Irene M.
Format: Artigo
Langue:Inglês
Publié: Cold Spring Harbor Laboratory Press 2000
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316617/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10817757/
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