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Two protein tyrosine phosphatases, Ptp2 and Ptp3, modulate the subcellular localization of the Hog1 MAP kinase in yeast

The MAP kinase Hog1 transiently accumulates in the nucleus upon activation. Although Hog1 nuclear export correlates with its dephosphorylation, we find that dephosphorylation is not necessary for export. Unexpectedly, a strain lacking the nuclear protein tyrosine phosphatase, Ptp2, showed decreased...

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Detalles Bibliográficos
Main Authors: Mattison, Christopher P., Ota, Irene M.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2000
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC316617/
https://ncbi.nlm.nih.gov/pubmed/10817757
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