Functional requirement of p23 and Hsp90 in telomerase complexes

Most normal human diploid cells have no detectable telomerase; however, expression of the catalytic subunit of telomerase is sufficient to induce telomerase activity and, in many cases, will bypass normal senescence. We and others have previously demonstrated in vitro assembly of active telomerase b...

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Hauptverfasser: Holt, Shawn E., Aisner, Dara L., Baur, Joseph, Tesmer, Valerie M., Dy, Marife, Ouellette, Michel, Trager, James B., Morin, Gregg B., Toft, David O., Shay, Jerry W., Wright, Woodring E., White, Michael A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 1999
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC316592/
https://ncbi.nlm.nih.gov/pubmed/10197982
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