Estrogen Induces c-myc Gene Expression via an Upstream Enhancer Activated by the Estrogen Receptor and the AP-1 Transcription Factor

c-myc oncogene is implicated in tumorigenesis of many cancers, including breast cancer. Although c-myc is a well-known estrogen-induced gene, its promoter has no estrogen-response element, and the underlying mechanism by which estrogen induces its expression remains obscure. Recent genome-wide studi...

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Detalhes bibliográficos
Main Authors: Wang, Chunyu, Mayer, Julie Ann, Mazumdar, Abhijit, Fertuck, Kirsten, Kim, Heetae, Brown, Myles, Brown, Powel H.
Formato: Artigo
Idioma:Inglês
Publicado em: Endocrine Society 2011
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Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165912/
https://ncbi.nlm.nih.gov/pubmed/21835891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2011-1037
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