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Poliovirus Switches to an eIF2-Independent Mode of Translation during Infection

Inhibition of translation is an integral component of the innate antiviral response and is largely accomplished via interferon-activated phosphorylation of the α subunit of eukaryotic initiation factor 2 (eIF2α). To successfully infect a host, a virus must overcome this blockage by either controllin...

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Hlavní autoři: White, James P., Reineke, Lucas C., Lloyd, Richard E.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165854/
https://ncbi.nlm.nih.gov/pubmed/21697471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00792-11
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