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The Papillomavirus E1 Helicase Activates a Cellular DNA Damage Response in Viral Replication Foci
The papillomavirus E1 and E2 proteins are essential for viral genome replication. E1 is a helicase that unwinds the viral origin and recruits host cellular factors to replicate the viral genome. E2 is a transcriptional regulator that helps recruit the E1 helicase to the origin and also plays a role...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3165833/ https://ncbi.nlm.nih.gov/pubmed/21734054 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00541-11 |
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