Potent and Broad Anti-HIV-1 Activity Exhibited by a Glycosyl-Phosphatidylinositol-Anchored Peptide Derived from the CDR H3 of Broadly Neutralizing Antibody PG16

PG9 and PG16 are two recently isolated quaternary-specific human monoclonal antibodies that neutralize 70 to 80% of circulating HIV-1 isolates. The crystal structure of PG16 shows that it contains an exceptionally long CDR H3 that forms a unique stable subdomain that towers above the antibody surfac...

全面介紹

Na minha lista:
書目詳細資料
Main Authors: Liu, Lihong, Wen, Michael, Wang, Weiming, Wang, Shumei, Yang, Lifei, Liu, Yong, Qian, Mengran, Zhang, Linqi, Shao, Yiming, Kimata, Jason T., Zhou, Paul
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2011
主題:
Vaccines and Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165811/
https://ncbi.nlm.nih.gov/pubmed/21715497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00520-11
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍