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CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex

By virtue of its control over major histocompatibility complex class II (MHC-II) gene expression, CIITA represents a key molecule in the regulation of adaptive immune responses. It was first identified as a factor that is defective in MHC-II deficiency, a hereditary disease characterized by the abse...

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Vydáno v:Genes Dev
Hlavní autoři: Masternak, Krzysztof, Muhlethaler-Mottet, Annick, Villard, Jean, Zufferey, Madeleine, Steimle, Viktor, Reith, Walter
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC316580/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10809673/
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