RNA Binding by a Novel Helical Fold of B2 Protein from Wuhan Nodavirus Mediates the Suppression of RNA Interference and Promotes B2 Dimerization

Wuhan nodavirus (WhNV) is a newly identified member of the Nodaviridae family with a bipartite genome of positive-sense RNAs. A nonstructural protein encoded by subgenomic RNA3 of nodaviruses, B2, serves as a potent RNA silencing suppressor (RSS) by sequestering RNA duplexes. We have previously demo...

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Hlavní autoři: Qi, Nan, Cai, Dawei, Qiu, Yang, Xie, Jiazheng, Wang, Zhaowei, Si, Jie, Zhang, Jiamin, Zhou, Xi, Hu, Yuanyang
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2011
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165748/
https://ncbi.nlm.nih.gov/pubmed/21734038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00785-11
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