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SCF(FBXO22) Regulates Histone H3 Lysine 9 and 36 Methylation Levels by Targeting Histone Demethylase KDM4A for Ubiquitin-Mediated Proteasomal Degradation

Reversible methylation of lysine residues has emerged as a central mechanism for epigenetic regulation and is a component of the “histone code,” which engenders histones with gene regulatory information. KDM4A is a histone demethylase that targets tri- and dimethylation marks on histone H3 lysines 9...

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Detalhes bibliográficos
Main Authors: Tan, Meng-Kwang Marcus, Lim, Hui-Jun, Harper, J. Wade
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165736/
https://ncbi.nlm.nih.gov/pubmed/21768309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05746-11
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