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Membrane Proteases and Aminoglycoside Antibiotic Resistance

We present genetic studies that help define the functional network underlying intrinsic aminoglycoside resistance in Pseudomonas aeruginosa. Our analysis shows that proteolysis, particularly that controlled by the membrane protease FtsH, is a major determinant of resistance. First, we examined the c...

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Bibliografiske detaljer
Main Authors: Hinz, Aaron, Lee, Samuel, Jacoby, Kyle, Manoil, Colin
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165699/
https://ncbi.nlm.nih.gov/pubmed/21764915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05133-11
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