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Membrane Proteases and Aminoglycoside Antibiotic Resistance

We present genetic studies that help define the functional network underlying intrinsic aminoglycoside resistance in Pseudomonas aeruginosa. Our analysis shows that proteolysis, particularly that controlled by the membrane protease FtsH, is a major determinant of resistance. First, we examined the c...

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Detalhes bibliográficos
Main Authors: Hinz, Aaron, Lee, Samuel, Jacoby, Kyle, Manoil, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165699/
https://ncbi.nlm.nih.gov/pubmed/21764915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05133-11
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