The Rhodanese Domain of ThiI Is Both Necessary and Sufficient for Synthesis of the Thiazole Moiety of Thiamine in Salmonella enterica

In Salmonella enterica, ThiI is a bifunctional enzyme required for the synthesis of both the 4-thiouridine modification in tRNA and the thiazole moiety of thiamine. In 4-thiouridine biosynthesis, ThiI adenylates the tRNA uridine and transfers sulfur from a persulfide formed on the protein. The role...

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Bibliographic Details
Main Authors: Martinez-Gomez, N. Cecilia, Palmer, Lauren D., Vivas, Eugenio, Roach, Peter L., Downs, Diana M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2011
Subjects:
Physiology and Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3165671/
https://ncbi.nlm.nih.gov/pubmed/21724998
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05325-11
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